Ctr copper transporter family protein

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August undefined, 2024

WebRecently it has been suggested that human Ctr1 (hCtr1) may act as a copper transporter in several tissues including the intestine. hCtr1 is a 190 amino acid protein and is predicted to have three transmembrane-spanning domains and exist in … WebApr 21, 2011 · The rice COPT-type gene family consists of seven members (COPT1 to COPT7). However, only two, COPT1 and COPT5, have been characterized for their functions in Cu transport. Results: All members of the rice COPT family have the conserved features of known COPT/Ctr-type Cu transporter genes.

Eukaryotic CTR Copper Uptake Transporters Require …

WebThe reported Cu transporters are mainly from the COPT/Ctr protein family. Cu might be co-transported by COPT2, COPT3, and COPT4 with COPT6. ... Yuan M, Li X, Xiao J, Wang S (2011) Molecular and functional analyses of COPT/Ctr-type copper transporter-like gene family in rice. BMC Plant Biol 11(1):69 WebA different class of transporter known as the SLC31 or Ctr family of proteins mediates cellular copper uptake. These high-affinity copper transporters exist in all eukaryotes … d and r waste codes

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WebMembers of the copper uptake transporter (CTR) family from yeast, plants, and mammals including human are required for cellular uptake of … WebCopper uptake is regulated by CTR (copper transporter) family of proteins, which are highly conserved. High affinity copper uptake is facilitated by Ctr1 and Ctr3 in Saccharomyces cerevisiae and ... birmingham city schools special education

Biochemical and Genetic Analyses of Yeast and Human High …

The SLC31 (Ctr) copper transporter family - PubMed

WebCtr copper transporter family. The redox active metal copper is an essential cofactor in critical biological processes such as respiration, iron transport, oxidative stress … WebApr 1, 2014 · Copper (Cu) is an essential micronutrient for all eukaryotes because it participates as a redox active cofactor in multiple biological processes, including mitochondrial respiration, photosynthesis, oxidative stress protection, and iron (Fe) transport. In eukaryotic cells, Cu transport toward the cytoplasm is mediated by the … birmingham city schools zoningWebJul 21, 2014 · The family of proteins responsible for the transport of Cu in the reduced form is the COPT transport protein (copper transporter protein). These proteins are formed by five... birmingham city schools teacher

"WebOct 1, 2024 · The moss Physcomitrium (Physcomitrella) patens is a bryophyte that provides genetic information about the adaptation to the life on land by early Embryophytes and is a reference organism for comparative evolutionary studies in plants. Copper is an essential micronutrient for every living organism, its transport across the plasma membrane is … " - Ctr copper transporter family protein

Ctr copper transporter family protein

A differential subcellular localization of two copper ... - ScienceDirect

WebStudies were conducted to determine distribution of the copper transporter, Ctr1, a transmembrane protein responsible for cellular copper uptake, in adult mice and in … WebDec 13, 2024 · Gene Summary Copper transporter 1A ( Ctr1A) encodes a plasma membrane protein that functions as a copper transporter. It is required to drive neuropeptide maturation during normal growth and development. [Date last reviewed: 2024-03-07] ( FlyBase Gene Snapshot ) All Summaries Gene Snapshot Gene Group Key …

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WebOct 19, 2015 · These transport proteins are thought to have evolved from ‘half-transporters’ containing a single repeat via gene duplication and subsequent fusion 28. … WebOct 30, 2024 · Among these, the main group is the COPT (COPper transporter)/Ctr (Copper transporter) proteins belonging to several protein families in diverse organisms (Puig and Thiele 2002). Another transporter type for Cu movement from cytosol into organelles in plants and humans is P-type adenosine triphosphate pump (Williams et al. …

WebMembers of the copper uptake transporter (CTR) family from yeast, plants, and mammals including human are required for cellular uptake of the essential metal copper. Based on biochemical data, CTRs have three … WebJul 24, 2024 · Naturally, this localization of the receptors requires the transport of monovalent copper from the plasma membrane via the cytoplasm to the apoproteins in the ER-Golgi membranes. The identity of the copper carriers involved in this task and their cellular routes are not yet completely known.

WebNational Center for Biotechnology Information WebMar 1, 2003 · Recently it has been suggested that human Ctr1 (hCtr1) may act as a copper transporter in several tissues including the intestine. hCtr1 is a 190 amino acid protein and is predicted to have three transmembrane-spanning domains and exist in the plasma membrane as a homo-trimer.

WebFeb 8, 2002 · This is the first report on the biochemical characterization of the human copper transporter hCtr1, which is important for understanding mechanisms for mammalian copper transport at the plasma membrane. The trace metal copper is an essential cofactor for a number of biological processes including mitochondrial oxidative …

WebFigure 1. Bioinformatic analysis identifies C. thermophilum copper transporters. A, model showing a homotrimeric Ctr1/Ctr3 family protein complex with key Cys and Met residues involved in Cu + transport connected with a dashed red circle and key Gly residues involved in trimer stability via transmembrane helical packing highlighted with a red box. … dandry company gmbhWebthe SLC31 or Ctr family of proteins mediates cellular copper uptake. These high-affinity copper transporters exist in all eukaryotes and their discovery has provided new insights … birmingham city schools spring break 2023WebMar 1, 2004 · A different class of transporter known as the SLC31 or Ctr family of proteins mediates cellular copper uptake. These high-affinity copper transporters exist in all … birmingham city schools virtualWebJan 5, 2024 · Enables copper ion transmembrane transporter activity. Involved in cellular copper ion homeostasis; copper ion transport; and regulation of heart rate. Located in plasma membrane. Is expressed in adult head. Orthologous to several human genes including SLC31A1 (solute carrier family 31 member 1). [provided by Alliance of … d and rvWebDec 1, 2015 · The COPT/Ctr family belongs to a highly conserved Ctr-like Cu transporter family. Most COPT/Ctr transporters contain 3 TMDs: TMD1, TMD2, and TMD3. The N terminus of most COPT/Ctr transporters includes methionine motifs involved in Cu binding that is important for facilitated import (Beaudoin et al., 2011). d and r village clifton park nyWebin copper transport is currently lacking. According to computer algorithm analyses, Ctr family members contain three mem-brane-spanning domains, within which most of protein se-quence similarity lies. Biochemical and microscopy experi-ments in yeast and human cells have suggested that Ctr family members are integral membrane proteins that ... d and r wholesaleWebApr 21, 2011 · The copper (Cu) transporter (COPT/Ctr) gene family has an important role in the maintenance of Cu homeostasis in different species. The rice COPT-type gene family consists of seven members (COPT1 to COPT7). However, only two, COPT1 and COPT5, have been characterized for their functions in Cu transport. Here we report the … d and s activewear