TīmeklisFunction. May be involved in axonal outgrowth as component of the network of molecules that regulate cellular morphology and axon guidance machinery. Able to … Tīmeklis2024. gada 2. febr. · INTRODUCTION. FEZ1 is an adaptor for the outward-directed microtubule (MT) motor, kinesin-1, and a hub protein that interacts with a range of other proteins (Bloom and Horvitz, 1997) (reviewed in Maturana et al., 2010; Teixeira et al., 2024).These combined functions mean that FEZ1 is involved in various biological …
Investigation of fasciculation and elongation protein ζ-1 (FEZ1) in ...
TīmeklisExperimental design: We examined FEZ1 expression in 17 non-small cell lung cancer (NSCLC), 19 small cell lung cancer (SCLC) cell lines, and 6 pairs of short-term … Tīmeklis2015. gada 30. dec. · The FEZ1 null mice exhibit hyperactivity and enhanced responsiveness to psychostimulants , supporting a po-tential contribution of FEZ1 dysfunction to SZ. Recently, additional evidence based on sequencing of DISC1 -interacting partner genes including FEZ1 revealed an increased burden of rare … griffiths manual
Differential expression of FEZ1/LZTS1 gene in lung cancers and …
TīmeklisAims: Fasciculation and elongation protein zeta-1 (FEZ1) is a critical regulator of dopaminergic neurone differentiation and dopamine release. However, to date, few studies evaluating the expression patterns of FEZ1 in Parkinson's disease (PD) have been reported. The aim of this study was to investigate the expression and cellular … Tīmeklis2016. gada 1. jūn. · Our findings suggest that perturbed FEZ1-mediated synaptic delivery of proteins arising from abnormal signalling potentially contributes to the … Tīmeklis2009. gada 19. nov. · The protein FEZ1 (fasciculation and elongation protein zeta 1) was initially described as an orthologue of the UNC-76 protein, which performs important functions in the neuronal development of C. elegans [].Later, it was observed that FEZ1 interacts with cytoskeleton elements, mainly α-tubulin [], and participates in … griffiths malta