Webb9 feb. 2010 · New studies have been published since the Cochrane review was conducted, including the Total Body Hypothermia (TOBY) trial, the largest randomised controlled … WebbThis multicentre, randomised trial investigated whether a reduction of body temperature by 3-4 degrees centigrade in full term infants with moderate or severe perinatal asphyxial …

Cerebral Function Monitoring - Royal Sussex County Hospital

Webb1 okt. 2009 · Background: Whether hypothermic therapy improves neurodevelopmental outcomes in newborn infants with asphyxial encephalopathy is uncertain. Methods: We performed a randomized trial of infants who were less than 6 hours of age and had a gestational age of at least 36 weeks and perinatal asphyxial encephalopathy. We … WebbEncephalopathy (TOBY) trial. Methods In the TOBY trial hypoxic–ischaemic encephalopathy was graded clinically according to the changes seen on amplitude … pentair manitowoc

Moderate hypothermia to treat perinatal asphyxial encephalopathy

WebbThe National Perinatal Epidemiology Unit (NPEU) is a multidisciplinary research unit based at the University of Oxford. Our work involves running randomised controlled trials, national surveillance programmes and surveys, confidential enquiries, aetiological studies and a disease register. The results of our research sit at the nexus of public and population … Webb1 juni 2014 · Clinical Trials of Adjuvant Therapies for Neonatal Encephalopathy. Because the incidence of death and disability remains high after treatment with cooling … WebbIn the TOBY trial, 325 infants with a gestational age of at least 36 weeks who had moderate-to-severe asphyxial encephalopathy and abnormal results on amplitude … todd blackledge wife picture